Karyopharm Therapeutics Inc. 401(k) Plan: Login, Facts & Contact Information

Karyopharm Therapeutics Inc. 401(k) Plan Facts

Plan name
KARYOPHARM THERAPEUTICS INC. 401(K) PLAN
Plan type
401(k) with employer contributions and profit sharing
Plan sponsor
KARYOPHARM THERAPEUTICS INC.
Participants
546 (284 active employees)
Former employees with a balance
219
Plan assets
$55,627,157 at Dec 31, 2024
Average account balance
$114,932 across 484 accounts
Employer contributions
$2,512,829 in plan year 2024 (26% of all contributions)
Recordkeeper
Fidelity Investments Institutional
Plan year
Jan 1, 2024 – Dec 31, 2024
Plan established
Jan 1, 2011
✓ Employer contributions— Automatic enrollment✓ Default investment for undecided participants✓ Participants choose their own investments— Self-directed brokerage window✓ Profit sharing— Company stock (ESOP)

Source: Form 5500 for plan year 2024 (Jan 1, 2024 – Dec 31, 2024), filed Jul 30, 2025. Public filing with the U.S. Department of Labor.

Money in and out in plan year 2024

  • $9.62 million went into the plan in contributions, $2.51 million of it from the employer (26%).
  • $7.41 million was paid out to participants.
  • Investment and other income added $7.44 million.
  • Administrative expenses were $62,878, about $130 per account.

How the Karyopharm Therapeutics Inc. 401(k) changed, 2019–2024

Plan yearParticipantsPlan assetsEmployer contributionsBenefits paid
2019302$16.7 million$2.11 million$2.26 million
2020420$26.5 million$2.48 million$2.17 million
2021507$39.0 million$2.86 million$4.89 million
2022558$36.0 million$3.08 million$5.21 million
2023597$46.1 million$3.21 million$9.01 million
2024546$55.6 million$2.51 million$7.41 million

Karyopharm Therapeutics Inc. 401(k) Contact Information

Phone
617-658-0600
Mailing address
85 WELLS AVENUE, SUITE 210, NEWTON MA 02459
Plan sponsor
KARYOPHARM THERAPEUTICS INC.
Employer identification number (EIN)
26-3931704
Plan number
001

Questions about the Karyopharm Therapeutics Inc. 401(k)

Does Karyopharm Therapeutics Inc contribute to the 401(k)?

Yes. The plan reports an employer contribution arrangement. In plan year 2024 the employer contributed $2.51 million, 26% of all contributions.

Does the Karyopharm Therapeutics Inc 401(k) have automatic enrollment?

No. The plan does not report automatic enrollment; employees enroll themselves.

How many people are in the Karyopharm Therapeutics Inc 401(k) plan?

546 participants at the start of plan year 2024, 284 of them active employees, and 219 former employees who still had money in the plan.

What is the average 401(k) balance at Karyopharm Therapeutics Inc?

About $114,932 per account: $55.6 million in plan assets across 484 accounts with a balance at the end of plan year 2024.

Who manages the Karyopharm Therapeutics Inc 401(k) accounts?

Fidelity NetBenefits (listed on the filing as FIDELITY INVESTMENTS INSTITUTIONAL) is the plan's recordkeeper, which is where participants log in to see their balance.

I no longer work at Karyopharm Therapeutics Inc. How do I access my 401(k)?

Your account stays with Fidelity NetBenefits after you leave, so you can log in with the same credentials. If your balance was small, the plan may have rolled it into an IRA in your name. If you can't find it, Beagle can locate it for you.

Related Companies
Headquarter: 1200 E. 14 MILE ROAD, MADISON HEIGHTS, MI, 480711421
Headquarter: 1225 GARRISON DRIVE, MURFREESBORO, TN, 37129
Headquarter: 155 HARLEM AVE, GLENVIEW, IL, 60025
Headquarter: 900 ASHWOOD PARKWAY STE. 700, ATLANTA, GA, 30338
Headquarter: 1 ECOLAB PLACE / EGH03, ST. PAUL, MN, 55102